Cat Respiratory Condition Treatments

Inhaled forms of steroid are preferred for long-term management

Inhaled vs Systemic Steroids

Inhaled forms of steroid are preferred for long-term management

Inhaled vs Systemic Steroids
Inhaled Steroids Systemic Steroids
Delivery Method Delivered exactly where needed: your cat's lungs Enter the bloodstream and are sent all around the body
Concentration Required 25x lower concentrations of steroid needed Higher doses needed to ensure some of it makes it to the lungs
Safety Safer Side effects can cause health and behavioral changes
Usage Duration Can be used for long-term disease control Only recommended for short-term use after a severe asthma attack
Ease of Administration Easier to administer - bonding moments can make it a positive experience Difficult to administer - hard to bond with pills or needles
Impact on Pet's Quality of Life Helps keep pets able and willing to play with their families Side effects can halt play and change the personality of your cat

Systemic Steroids

Side Effects of Systemic Steroids

The goal of oral steroid treatment is to find the lowest dose possible and use it for the shortest period of time.

Common Side Effects

These side effects may reduce your cat's quality of life and the family relationship.

  • Lethargy/fatigue (no energy to play)
  • Change in behavior (such as aggression)
  • Suppressed immune system function
  • Increased risk of bacterial, fungal, and urinary infections
  • Diabetes
  • Weight gain / obesity
  • Vomiting, diarrhea
  • Loss of bladder control
  • Poor wound healing
  • Cushing's disease
  • Hair loss and skin or coat changes
  • Increased blood pressure
  • Stomach ulcers

Impact on Quality of Life

Cats who are lethargic or have a change in behaviour may be unable or unwilling to play and may no longer seem like the pet you once knew.

Treatment Path

Treatment Path and Dosing Guidelines for Feline Asthma and Canine Bronchitis

Ensure patient can breathe

  • Immediately dilate airways to provide respiratory relief
  • Provide injectable steroid and either inhaled or injectable bronchodilator
  • Administer injectable medications in clinic
  • Inhaled bronchodilator (i.e. albuterol / salbutamol) may be administered in clinic or at home by owner. Owners unable to regain control at home should bring their pet to the clinic for veterinary care

Medication

Medication Image

Dosing Guideline

Medication ≤ 20 kg (44.1 lb) > 20 kg (44.1 lb)
Dexamethasone 0.1-0.5 mg/kg IM or IV 0.1-0.5 mg/kg IM or IV
Terbutaline 0.01 mg/kg IM or SC in clinic 0.01 mg/kg IM or SC in clinic
Albuterol/Salbutamol 1-2 puffs every 30 minutes for ≤ 4-5 hours 1-2 puffs every 30 minutes for ≤ 4-5 hours

Notes

Owners unable to regain control at home should bring their pet to the clinic for veterinary care

Ensure patient can breathe

  • Provide 10-day, short-term course of systemic steroids

Medication

Medication Image

Dosing Guideline

Medication Cats Dogs
Prednisolone 1-2 mg/kg (every 24 hours) -
Prednisone - 0.5-1 mg/kg every 24 hours

Notes

  • Review environmental factors and make modifications to reduce potential triggers
  • Ensure pet owners understand corticosteroids are considered a mainstay of treatment and may be administered orally or via injection or inhalation; inhaled forms help limit systemic absorption (see Adverse Effects of Systemic Steroids)
  • Owners already providing inhaled steroids to their pet and who treated exacerbation with albuterol can continue with inhaled steroid therapy; those currently using other forms may consider transitioning to inhaled corticosteroids

Ensure patient can breathe

  • Taper systemic steroids and introduce inhaled steroids
  • Overlap systemic and inhaled therapy for 2 weeks

Medication

Medication Image

Dosing Guideline

Medication ≤ 20 kg (44.1 lb) > 20 kg (44.1 lb)
Fluticasone 1 puff (110 μg) every 12 hours 1 puff (220 μg) every 12 hours
Fluticasone + salmeterol 1 puff (115 μg/21 μg) every 12 hours 1 puff (230 μg/21 μg) every 12 hours

*Cats with more serious disease may require 220 μg every 12 hours

Notes

Inhaled steroids may require 2 weeks to take effect

Ensure patient can breathe

  • Use maintenance therapy to control inflammation and prevent exacerbation
  • Continue daily therapy for management of clinical signs
  • Cat owners can administer inhaled bronchodilators during flare-ups secondary to exposure to triggers

Medication

Medication Image

Dosing Guideline

Medication ≤ 20 kg (44.1 lb) > 20 kg (44.1 lb)
Fluticasone 1 puff (110 μg) every 12 hours 1 puff (220 μg) every 12 hours
Fluticasone + salmeterol 1 puff (115 μg/21 μg) every 12 hours 1 puff (230 μg/21 μg) every 12 hours
Albuterol or salbutamol (SABA) 1 to 2 puffs as needed (cats) -

*Cats with more serious disease may require 220 μg every 12 hours

Notes

  • Albuterol is a rescue medication and should not be used as monotherapy
  • Dogs have not been shown to experience bronchoconstriction
  • Little evidence exists for effectiveness of albuterol therapy to manage canine bronchitis

Types of Inhaled Medication

Treatment for emergencies or long-term management.

Asthma in animals is treated with corticosteroids and bronchodilators, similar to human treatments but with different doses and administration for cats, dogs, and horses.

Bronchodilators are medications used to expand the airways. Short acting bronchodilators are commonly referred to as rescue medications because they act quickly and may be administered during an asthma attack.

  • Opens airways by relaxing smooth muscles to reduce bronchoconstriction
  • May be used symptomatically to help with coughing flare-ups
  • Effects usually only last 4-6 hours
  • Does not treat underlying inflammation; inhaled corticosteroids are the mainstay for long-term management and control

Drug Names

  • Albuterol
  • Salbutamol
  • Ventolin
  • ProAir
  • Proventil

Bronchodilators are medications used to expand the airways. Short acting bronchodilators are commonly referred to as rescue medications because they act quickly and may be administered during an asthma attack.

  • Opens airways by relaxing smooth muscles to reduce bronchoconstriction
  • May be used symptomatically to help with coughing flare-ups
  • Effects usually only last 4-6 hours
  • Does not treat underlying inflammation; inhaled corticosteroids are the mainstay for long-term management and control

Drug Names

  • Albuterol
  • Salbutamol
  • Ventolin
  • ProAir
  • Proventil

Bronchodilators are medications used to expand the airways. Short acting bronchodilators are commonly referred to as rescue medications because they act quickly and may be administered during an asthma attack.

  • Opens airways by relaxing smooth muscles to reduce bronchoconstriction
  • May be used symptomatically to help with coughing flare-ups
  • Effects usually only last 4-6 hours
  • Does not treat underlying inflammation; inhaled corticosteroids are the mainstay for long-term management and control

Drug Names

  • Albuterol
  • Salbutamol
  • Ventolin
  • ProAir
  • Proventil

Prepare for the vet

What To Expect At The Vet's Office

Before visiting your vet, take note of any other signs or symptoms your cat has shown in addition to the cough.

Preparing for Your Vet Visit

If possible, try to take a video of your cat coughing at home to show the vet. Your vet will want to know as much as possible in order to properly diagnose and treat your pet.

Although relatively common, coughing in cats can be a sign of a more serious issue that can be life-threatening in some cases. If you are unsure if your cat's cough warrants a visit to the vet, always err on the side of caution and take them regardless.

Questions Your Vet Might Ask

  • How long have the symptoms been present?
  • Is the cough wet or dry?
  • Have you noticed any other symptoms besides the cough?
  • Does your cat go outside?
  • Is your cat receiving preventative treatment for parasitic worms?
  • Is your cat more lethargic than usual?
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